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Back to Basics.

Yesterday, after two weeks of clingy lows and then some unreasonable high blood sugars, I took a look at my meter average and saw a climb in numbers that I was not happy with.  Could it really be the switch from Humalog to Novolog two and a half weeks ago?  Does the difference actually matter?  Some say yes, some say no, and some teeter in the space between.

I'm not sure if I'm a definitive "yes" or "no" yet, but I do know that I have no room for stubborn 280 mg/dL's or nights where I'm low three times over.  Could be coincidence, could be my personal response to the insulin change, but either way, I could feel my hard work eeking away with every meter beep.  I'm going back to basics (thankfully, my Humalog supply wasn't exhausted) and contacting my mail order pharmacy today to see if there's any chance they'll take back the three month's worth of accidental Novolog and swap it out for the insulin I'm familiar with.

Back to Humalog for now.

I don't mind spending time figuring things out and making adjustments, but sometimes, it's not worth it to me.  Especially when my A1C is holding steady at a range that I'm happy to hang on to.  I hope the pharmacy agrees.


If it's psychological, then it's at least producing a physiological response. I went through the same thing switching from Apidra to Humalog December-February. Weeks of "clingy lows" and vicious highs! Switching back to my insulin of choice immediately leveled me out. Looking at my Dexcom charts, it was not possibly my imagination.

That's how I feel about Novolog. With Humalog, I may as well be injecting water. I don't know what the difference is, really. Sorry you had so many issues with it.

must be "luck of the draw"
(I know you love puns =)

I would be incredibly surprised if the pharmacy takes back the meds. What might happen, is that they send out replacements and ask you to discard the wrong stuff.

I would not want to be on the receiving end of meds that were in someone else's possession, especially something that needs refrigeration.

Hi Kerri,
I have to ask a question. Have you ever read the paper notice contained within each insulin bottle?
The reason that I am asking the question is to point out the fact that when each insulin reaches the optimum peaking period is different. Further, the timing of how long after taking the product that the insulin curve will continue to "lower" blood glucose is different. Hence there could be a need to revise one's basal rates for a 24 hour period. Sleeping is the one time frame during the day that the exercise and the food components are not present. It is the period of insulin and blood glucose only. However, our bodies still running through periods of dreaming, rebuilding and repairing our multiple systems. Our insulin needs through sleep periods can also change based upon other factors. Hope this helps and as always have a great day.

You gave it a shot in hopes of better BGs. I think everyone responds differently to different insulins. My daughter had continuous highs on Humalog. We tried Apidra and got way too many lows in 1 day. For her Novolog is just right. For you Humalog's your #1. Glad there are 3 different fast acting insulins to try now. I hope the pharmacy will help you out! =)

When I had this problem, they wouldn't take the Apidra back but they were happy to fill a Rx for Humalog (since it's technically a different prescription). Sadly that meant two 3-month supply copays in one month. I was not a happy camper.

I hope the switch back to Humalog helps return everything to normal - it sucks to feel like you're losing control!

Maybe also think about giving the novolog another try in a month or so if you keep it (or are forced to by your pharmacy)? I did that recently when switching from novolog to apidra. I had a tough time with my first bottle of apidra, although in retrospect I had wrongly assumed that I could just switch out every unit of novolog with one unit of apidra.

After doing some research, I discovered that doses seemed to be all over the map -- for some people it was a 1-1 ratio, others needed much more apidra than novolog, and vice versa. Proving once again, as does your experience, that everyone's diabetes is different.

So I went back to my novolog for a month and tracked my carbs and insulin even more closely than usual. Based on that information I was able to start up the apidra again, with some targeted adjustments to my basals and boluses. The transition went much more smoothly the second time.

Of course, you may also decide "if it ain't broke, don't fix it." Maybe your time off the humalog was enough to kick whatever resistance your body may have built up over the years!

I don't have to tell you this, but please, go with what works. We have enough to deal with already without giving up something that's helpful to us for something that's less helpful. Good luck with the switch back.

Oh yes, I think it definitely could be the case. My endo and I did a lot of work trying me on different insulin brands before we concluded that for me, Apidra is the way to go.

I hope your pharmacy hooks you up without giving you a hard time!!

Similarly, I have been wondering about a switch in pumps. I still wear the Ping, but got a new one about a month and a half ago. Nothing else has changed, but like you, my numbers are consistently higher. I have double checked to make sure all my basal rates are the same, which they are. Wondering if anyone else has had to bump up their rates when switching to a new pump?

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